Nick Reiner's schizophrenia meds made him 'erratic,' sources say

Jami Ganz, New York Daily News on Dec 19, 2025

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A new report says Nick Reiner has a diagnosis of schizophrenia and that his behavior became “erratic and dangerous” due to a medication change in the weeks before he allegedly killed his parents Rob and Michele Reiner at their home in Los Angeles' Brentwood neighborhood.

The 32-year-old, who is charged with two counts of first-degree murder in the Dec. 14 slayings, was “erratic and dangerous” with the recent shift in medication, as doctors tried to stabilize him, two sources with direct knowledge told TMZ.

Despite the change and his recent stint at a $70,000-a-month Los Angeles rehabilitation center, Nick’s “alarming” behavior continued.

The sources added that his substance abuse, which began in adolescence, only exacerbated the deterioration of his mental health.

Nick’s younger sister Romy, 28, found the body of their 78-year-old father and was later notified that their mother, reported to be both 68 and 70, had also been killed.

Nick was arrested later Sunday and charged Tuesday. If convicted, he could face life in prison without parole or the death penalty. His arraignment has been scheduled for Jan. 7.

Nick has spoken openly about his struggles with addiction and homelessness over the years, which culminated in 2015’s semi-autobiographical “Being Charlie,” co-written by Nick and directed by his father.

The late Reiner even told NPR’s “Fresh Air” in September of this year that Nick was in a “really good place” and hadn’t “been doing drugs for over six years.”

According to multiple accounts, The “Princess Bride” filmmaker and Nick got into a “very loud argument” at Conan O’Brien’s holiday party the night before Reiner and his wife were fatally stabbed.

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